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Was the Omicron variant avoided?It May Reduce Vaccine Success Around the World | Mercile

Me An epidemiologist working in global health, he has been working in the field of vaccines for nearly 15 years. The scientific success of Sars-CoV-2 vaccine development was unrealistic, but the pandemic and unfair access to the vaccine discouraged me.

Australia is a success story worth celebrating, with two Covid-19 vaccinations reaching nearly 90% coverage. Covid-19 vaccination has already proven to be very effective in controlling large-scale community infections in the following situations: New South WalesRapid deployment at high levels of initial dose range, along with other public health measures, helped bend the curve.

However, the majority of low- and middle-income countries are vaccinated against only a small part of their population. NS analysis It suggests that 66% of people in high-income countries are fully vaccinated, while only 2.5% of the population in low-income countries are fully protected.

In many situations, even health care workers have not yet been vaccinated, and the country’s front-line defenses are very weak. With more than 3.5 billion people waiting for the first dose of the vaccine worldwide, many high-income countries have introduced boosters or third doses to the entire population along with pediatric vaccines.

The barriers to vaccination of people in low-income countries are primarily due to supply issues, and the doses available to them are negligible. There are other ongoing challenges, such as cold chain cold storage, distribution logistics, vaccine hesitation, and a shortage of healthcare professionals to administer vaccines in some environments, but the biggest barriers are associated with dose shortages. ..

The world is hearing the emergence of a new variant of concern, Omicron. It was first detected in Gauteng, South Africa, but the variant did not necessarily start there. It ’s still early days, WHO Technical Advisory Group on the Evolution of the Sars-CoV-2 Virus The alarm has occurred for several reasons. Early epidemiological data on cases in Gauteng, one of South Africa’s most populous regions, indicate that the strain appears to be spreading more rapidly than the rest of the country, giving Omicron the “S gene.” It suggests that there are new combinations of multiple mutations, including. It produces peaplomers and exerts an apparent ability to surpass delta variants.

According to science, we could have avoided the emergence of this new variant of concern. Viral mutations are part of natural selection and are common. When a virus invades a cell, it makes a copy of itself, which can disappear and infect other cells, infecting others.

“Errors” or mutations may occur during this process of copying non-immune individuals. Also, these mutations may provide a competitive advantage for the virus to spread from non-immune to another.

However, if a person is already immune (eg from vaccination), the virus cannot spread among people and prevents the emergence of new variants.

The emergence of each new mutant of concern may affect our public health measures, strain testing methods, and whether current vaccines work. The emergence of new variants that escape existing vaccines could significantly reduce the success of Covid-19 vaccination worldwide.

It is premature to say whether this is the case for Omicron, or whether there are “real” differences in properties with respect to its transmission, the ability to cause severe disease, and whether it will replace the SARS delta mutant. ――It reminds you in a timely manner that more people in the world are needed to be vaccinated with CoV-2 and Covid-19.

Vaccination is one of the best ways to avoid the emergence of new variants.

Experts in this field have been advocating increased vaccine equity around the world for several months, low through increased supply by Covax and the abandonment of intellectual property holding recipes for how vaccines are made. Income countries have easier access to vaccines. Greater manufacturing capacity in low and middle income countries.

Vaccination of poor people who experience the worst effects of Covid-19 at the same pace as the world’s population, especially rich countries, is important for several reasons.

First, it’s more equitable and ethical.Second, economic estimates from UN estimates are for low- and middle-income countries. Will suffer a loss of $ 12 trillion by 2025And third, the scientific case for immunizing the world is solid.

Preparing to enter the third year of the pandemic has significant implications for measles, tuberculosis, HIV and other routine medical services in other medical programs around the world, especially in low- and middle-income countries. I have. In addition, it can have a more serious impact on people in poverty.

As countries embark on booster, adolescent and pediatric vaccination programs, faster policy-level solutions are needed to increase vaccine supply in low- and middle-income countries.

The current approach is not optimal.

Was the Omicron variant avoided?It May Reduce Vaccine Success Around the World | Mercile

Source link Was the Omicron variant avoided?It May Reduce Vaccine Success Around the World | Mercile

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