Pfizer has begun a study comparing the original COVID-19 vaccine with a dose specifically adjusted to match the highly contagious Omicron variant.
Pfizer and its partner BioNTech announced their investigation on Tuesday.
COVID-19 vaccine manufacturers are updating their shots to better match Omicron in case global health authorities determine that changes are needed.
Omicrons are more likely to cause infection in vaccinated individuals than previous variants, but it is not yet clear if the vaccine recipe needs to be changed.
The original vaccine still provides excellent protection against serious illness and death. Studies in the United States and elsewhere have shown that adding booster doses enhances its protection and increases the likelihood of avoiding mild infections.
“This protection may help address Omicron and new variants in the future, in case this protection diminishes over time,” said Kathrin Jansen, head of vaccine research at Pfizer, in a statement. I am aware of that. “
A new US study enrolls up to 1420 healthy adults aged 18-55 years to test Omicron-based shots updated for use in boosters or primary vaccinations.
Researchers will investigate the safety of the conditioned vaccine and how it improves the immune system compared to the original shot.
In one study group, about 600 volunteers who received two doses of the current Pfizer vaccine three to six months ago receive one or two Omicron-based injections as boosters.
Another 600 people who have already been vaccinated with the Pfizer vaccine three times will receive a fourth dose of either the regular vaccine or an Omicron-compatible version.
In this study, unvaccinated volunteers are enrolled and vaccinated three times with an omicron-based vaccine.
Pfizer studying shots targeting Omicron
Source link Pfizer studying shots targeting Omicron