A spark of innovation in cancer research

After finishing training as a clinician Professor Mark Dawson When it came to treating cancer, I was dissatisfied with the fact that I couldn’t answer many questions. Why did two people of the same age with the same cancer who looked the same under the microscope and received the same treatment showed such different treatment results, one responding well and the other responding poorly? mosquito.

From the desire to find answers to such questions, Professor Dawson General John Monash Foundation — An organization established to support outstanding Australian students with graduate scholarships for study abroad. This program aims to foster leadership, expertise and an international network and build Australia’s capabilities for the future. With this scholarship, Professor Dawson went to Cambridge University in the United Kingdom to earn a PhD in epigenetics and worked to better understand different cancers and new approaches to treating them.

“Without the Sir John Monash Foundation, I wouldn’t be in place today,” said Professor Dawson. “This scholarship gave me the opportunity to go anywhere in the world, learn from the best people, work with them and pursue my career.”

Professor Dawson explained that his current approach to cancer treatment revolves around five pillars: surgery, chemotherapy, targeted therapy, radiation therapy, and immunotherapy. This is the latest and most promising therapy that can leverage a unique immune system to fight cancer cells.

“In recent years, we have gained a better understanding of the disease. We have a better understanding of what mutations exist and how they cause certain cancers. Explore the special functions of certain cells. This allowed us to develop more targeted treatments. Asking questions and looking for answers is what advances scientific discovery. “

Current, Peter McCallum Cancer Center And that University of Melbourne Cancer Research Center, Professor Dawson runs a group of 26 researchers trained in cancer epigenetics. He also co-leads the Cancer Biology and Therapy Program, which runs 13 different laboratories.

“This lab uses curiosity-based science to make discoveries that can help with better treatments,” says Professor Dawson.

“We need curiosity to innovate and move forward.”

Professor Dawson’s work has helped identify new treatment strategies for several cancers and establish clinical trials with epigenetic therapies.

Researchers in Professor Dawson’s lab are working to gain a better molecular understanding of the role that epigenetic regulators play in the initiation and maintenance of cancer and to discover the mechanisms by which malignant tumors evade therapeutic pressure. We hope that these findings will lead to a personalized approach to advancing clinical care.

A diverse team of clinicians and scientists has extensive expertise across biochemistry, cell biology, molecular biology, genomics, chemical biology, immunology, animal models of illness, and bioinformatics. This interdisciplinary approach is considered important in pursuing curiosity-driven innovation in cancer treatment.

A spark of innovation in cancer research

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